CSRP1
Cysteine and glycine-rich protein 1
Protein Summary
Could play a role in neuronal development. This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]
- ENST00000340006
- ENSP00000345079
- ENSG00000159176
- ENST00000367306
- ENSP00000356275
- ENST00000532460
- ENSP00000434147
- ENST00000533432
- ENSP00000436792
- CSRP
- CYRP
- CRP
- CRP1
- CSRP
- CYRP
- D1S181E
- HEL-141
- HEL-S-286
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.99 | ||
kinase perturbation | 0.98 | ||
disease perturbation | 0.97 | ||
PubMedID | 0.97 | ||
transcription factor binding site profile | 0.84 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 60.05 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 278 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 60.05 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 278 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0