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Tbio
AMY2B
Alpha-amylase 2B

Protein Summary
Description
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas. [provided by RefSeq, Jun 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361355
  • ENSP00000354610
  • ENSG00000240038
  • ENST00000477657
  • ENSP00000433347
  • ENST00000610648
  • ENSP00000481588

Symbol
  • HXA
  • AMY2
  • AMY3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.97
cell line
0.6
drug
0.57
tissue sample
0.51
metabolite
0.45


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 88.01   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 190   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 88.01   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 190   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P19961-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (7)
Digestion (R-HSA-8935690)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Digestion
Reactome
Digestion and absorption
Reactome
Digestion of dietary carbohydrate
Name
Explore in Pharos
Explore in Source
Digestion
Digestion and absorption
Digestion of dietary carbohydrate
Protein-Protein Interactions (52)
1 – 10 of 52
AMY2A
Tclin
Family:  Enzyme
Novelty:  0.00132709
p_int:  1
Score:  0.806
Data Source:  BioPlex,STRINGDB
MGAM2
Tdark
Family:  Enzyme
Novelty:  0.03471933
Score:  0.984
Data Source:  STRINGDB
MGAM
Tclin
Family:  Enzyme
Novelty:  0.00045865
Score:  0.964
Data Source:  STRINGDB
SI
Tchem
Family:  Enzyme
Novelty:  0.00048694
Score:  0.957
Data Source:  STRINGDB
GBE1
Tbio
Family:  Enzyme
Novelty:  0.00233237
Score:  0.935
Data Source:  STRINGDB
GANC
Tchem
Family:  Enzyme
Novelty:  0.02123234
Score:  0.918
Data Source:  STRINGDB
GAA
Tclin
Family:  Enzyme
Novelty:  0.0063246
Score:  0.869
Data Source:  STRINGDB
AGL
Tbio
Novelty:  0.00166875
Score:  0.836
Data Source:  STRINGDB
PYGB
Tchem
Family:  Enzyme
Novelty:  0.00224148
Score:  0.821
Data Source:  STRINGDB
PYGM
Tchem
Family:  Enzyme
Novelty:  0.00507768
Score:  0.817
Data Source:  STRINGDB
Publication Statistics
PubMed Score  88.01

PubMed score by year
PubTator Score  22.9

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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