CD58
Lymphocyte function-associated antigen 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cellular component | 0.8 | ||
small molecule perturbation | 0.74 | ||
tissue | 0.65 | ||
histone modification site profile | 0.63 | ||
transcription factor binding site profile | 0.63 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell surface interactions at the vascular wall | ||||
Reactome | Hemostasis | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | Neutrophil degranulation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell surface interactions at the vascular wall | ||||
Hemostasis | ||||
Immune System | ||||
Innate Immune System | ||||
Neutrophil degranulation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
6 | 4 | 0 | 1.3 | 97.8 | |||||
myeloid white cell count | 1 | 1 | 1 | 81.9 | |||||
primary biliary cirrhosis | 1 | 1 | 0 | 1.3 | 54.4 | ||||
diastolic blood pressure | 1 | 1 | 1 | 29 | |||||
leukocyte count | 1 | 1 | 1 | 26.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.3 | 97.8 | |||||
myeloid white cell count | 1 | 81.9 | |||||
primary biliary cirrhosis | 0 | 1.3 | 54.4 | ||||
diastolic blood pressure | 1 | 29 | |||||
leukocyte count | 1 | 26.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | CD58 molecule | VGNC:5014 | 457154 | |||||
Macaque | CD58 molecule | 710732 | ||||||
Horse | CD58 molecule | VGNC:50818 | 100066062 | |||||
Cow | CD58 molecule | VGNC:27040 | 782186 | |||||
Pig | CD58 molecule | 396702 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | CD58 molecule | |||||
Macaque | CD58 molecule | |||||
Horse | CD58 molecule | |||||
Cow | CD58 molecule | |||||
Pig | CD58 molecule | |||||
PMID | Year | Title |
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