PFKL
ATP-dependent 6-phosphofructokinase, liver type
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.99 | ||
disease perturbation | 0.87 | ||
transcription factor perturbation | 0.84 | ||
interacting protein | 0.76 | ||
hub protein | 0.75 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Glucose metabolism | ||||
Reactome | Glycolysis | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Reactome | Metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Glucose metabolism | ||||
Glycolysis | ||||
Immune System | ||||
Innate Immune System | ||||
Metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
Addison disease | 1 | 2 | 0 | 2.8 | 88.2 | ||||
eosinophil count | 3 | 2 | 3 | 85.1 | |||||
eosinophil percentage of leukocytes | 2 | 2 | 2 | 82.2 | |||||
HbA1c measurement | 1 | 3 | 3 | 67.4 | |||||
2 | 1 | 0 | 1.6 | 61.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
Addison disease | 0 | 2.8 | 88.2 | ||||
eosinophil count | 3 | 85.1 | |||||
eosinophil percentage of leukocytes | 2 | 82.2 | |||||
HbA1c measurement | 3 | 67.4 | |||||
0 | 1.6 | 61.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | phosphofructokinase, liver type | VGNC:7549 | 458602 | |||||
Mouse | MGI:97547 | 18641 | ||||||
Rat | RGD:3311 | 25741 | ||||||
Dog | phosphofructokinase, liver type | VGNC:44446 | 487797 | |||||
Horse | phosphofructokinase, liver type | VGNC:21341 | 100056927 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | phosphofructokinase, liver type | |||||
Mouse | ||||||
Rat | ||||||
Dog | phosphofructokinase, liver type | |||||
Horse | phosphofructokinase, liver type | |||||
PMID | Year | Title |
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