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Tbio
TAL1
T-cell acute lymphocytic leukemia protein 1

Protein Summary
Description
Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000294339
  • ENSP00000294339
  • ENSG00000162367
  • ENST00000371884
  • ENSP00000360951

Symbol
  • BHLHA17
  • SCL
  • TCL5
  • SCL
  • TCL5
  • tal-1
  • bHLHa17
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
hub protein
0.97
biological process
0.95
molecular function
0.95
gene perturbation
0.81
PubMedID
0.8


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 369.51   (req: < 5)
Gene RIFs: 74   (req: <= 3)
Antibodies: 671   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 369.51   (req: >= 5)
Gene RIFs: 74   (req: > 3)
Antibodies: 671   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 44
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0