TAL1
T-cell acute lymphocytic leukemia protein 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 0.97 | ||
biological process | 0.95 | ||
molecular function | 0.95 | ||
gene perturbation | 0.81 | ||
PubMedID | 0.8 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Developmental Biology | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | RNA Polymerase II Transcription | ||||
Reactome | RUNX1 regulates transcription of genes involved in differentiation of HSCs | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Developmental Biology | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
RNA Polymerase II Transcription | ||||
RUNX1 regulates transcription of genes involved in differentiation of HSCs | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 1 | 1 | 1 | 85.4 | |||||
red blood cell distribution width | 2 | 2 | 2 | 71.4 | |||||
mean platelet volume | 2 | 2 | 2 | 70.1 | |||||
body mass index | 4 | 2 | 4 | 69.6 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 48.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 1 | 85.4 | |||||
red blood cell distribution width | 2 | 71.4 | |||||
mean platelet volume | 2 | 70.1 | |||||
body mass index | 4 | 69.6 | |||||
mean reticulocyte volume | 1 | 48.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:98480 | 21349 | ||||||
Rat | RGD:1306748 | 313507 | ||||||
Dog | TAL bHLH transcription factor 1, erythroid differentiation factor | VGNC:47096 | 610331 | |||||
Cow | TAL bHLH transcription factor 1, erythroid differentiation factor | VGNC:35588 | 518657 | |||||
Opossum | TAL bHLH transcription factor 1, erythroid differentiation factor | 100023410 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Dog | TAL bHLH transcription factor 1, erythroid differentiation factor | |||||
Cow | TAL bHLH transcription factor 1, erythroid differentiation factor | |||||
Opossum | TAL bHLH transcription factor 1, erythroid differentiation factor | |||||
PMID | Year | Title |
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