IFNAR1
Interferon alpha/beta receptor 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.93 | ||
hub protein | 0.85 | ||
transcription factor perturbation | 0.84 | ||
cell type or tissue | 0.82 | ||
transcription factor binding site profile | 0.82 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Immune System | ||||
Reactome | Interferon Signaling | ||||
Reactome | Interferon alpha/beta signaling | ||||
Reactome | Regulation of IFNA signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytokine Signaling in Immune system | ||||
Immune System | ||||
Interferon Signaling | ||||
Interferon alpha/beta signaling | ||||
Regulation of IFNA signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
2 | 1 | 0 | 1.1 | 67.8 | |||||
interleukin-10 receptor B measurement | 1 | 1 | 1 | 64 | |||||
COVID-19 | 1 | 1 | 0 | 1.2 | 52.7 | ||||
eosinophil count | 1 | 1 | 1 | 42.3 | |||||
eosinophil percentage of leukocytes | 1 | 1 | 1 | 38.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.1 | 67.8 | |||||
interleukin-10 receptor B measurement | 1 | 64 | |||||
COVID-19 | 0 | 1.2 | 52.7 | ||||
eosinophil count | 1 | 42.3 | |||||
eosinophil percentage of leukocytes | 1 | 38.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | interferon alpha and beta receptor subunit 1 | VGNC:7183 | 458516 | |||||
Macaque | interferon alpha and beta receptor subunit 1 | 699604 | ||||||
Mouse | MGI:107658 | 15975 | ||||||
Rat | RGD:1305399 | 288264 | ||||||
Dog | interferon alpha/beta receptor 1 | 609830 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | interferon alpha and beta receptor subunit 1 | |||||
Macaque | interferon alpha and beta receptor subunit 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | interferon alpha/beta receptor 1 | |||||
PMID | Year | Title |
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