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Tdark
ZNF8
Zinc finger protein 8

Protein Summary
Description
Transcriptional repressor. May modulate BMP and TGF-beta signal transduction, through its interaction with SMAD proteins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000621650
  • ENSP00000477716
  • ENSG00000278129

Symbol
  • HF.18
  • Zfp128
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.87
co-expressed gene
0.76
cell type or tissue
0.69
cell line
0.6
protein domain
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.77   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 66   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.77   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 66   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Non-traceable Author Statement (NAS)
UniProtKB
Non-traceable Author Statement (NAS)
UniProtKB
Protein-Protein Interactions (17)
1 – 10 of 17
VWCE
Tbio
Novelty: 0.10129635
p_int: 0.99989799
p_ni: 5.31e-7
p_wrong: 0.000101479
Score: 0.251
Data Source: BioPlex,STRINGDB
PTPN12
Tchem
Family: Enzyme
Novelty: 0.01537047
Score: 0.628
Data Source: STRINGDB
GFER
Tchem
Family: Enzyme
Novelty: 0.00073821
Score: 0.594
Data Source: STRINGDB
EPHB2
Tchem
Family: Kinase
Novelty: 0.00187689
Score: 0.55
Data Source: STRINGDB
MSH6
Tbio
Family: Epigenetic
Novelty: 0.00148002
Score: 0.544
Data Source: STRINGDB
MSH3
Tbio
Novelty: 0.00139708
Score: 0.531
Data Source: STRINGDB
TPST2
Tbio
Family: Enzyme
Novelty: 0.03075981
Score: 0.501
Data Source: STRINGDB
RSPRY1
Tdark
Novelty: 0.46153846
Score: 0.478
Data Source: STRINGDB
ODF4
Tbio
Novelty: 0.14671557
Score: 0.476
Data Source: STRINGDB
FAM71C
Tdark
Score: 0.475
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.77

PubMed score by year
PubTator Score  2.6

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer