Protein Summary
May be involved in transcriptional regulation. This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions. [provided by RefSeq, Jul 2008]
- ENST00000354959
- ENSP00000347045
- ENSG00000198521
- ENST00000594012
- ENSP00000469578
- ENST00000595461
- ENSP00000469645
- ENST00000598381
- ENSP00000470275
- KOX27
- ZNF39
- ZNF39L1
- HTF6
- KOX27
- ZNF39L1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
microRNA | 0.92 | ||
histone modification site profile | 0.82 | ||
gene perturbation | 0.72 | ||
disease perturbation | 0.62 | ||
cell type or tissue | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.61 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 84 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.61 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 84 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0