You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
ZNF3
Zinc finger protein 3

Protein Summary
Description
Involved in cell differentiation and/or proliferation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000299667
  • ENSP00000299667
  • ENSG00000166526
  • ENST00000303915
  • ENSP00000306372
  • ENST00000413658
  • ENSP00000399951
  • ENST00000424697
  • ENSP00000415358

Symbol
  • KOX25
  • A8-51
  • HF.12
  • KOX25
  • PP838
  • Zfp113
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.86
PubMedID
0.66
transcription factor
0.65
cell type or tissue
0.64
histone modification site profile
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.99   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.99   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (33)
1 – 10 of 33
SHCBP1
Tbio
Novelty:  0.09160318
p_int:  0.999417243
p_ni:  0.000582756
p_wrong:  1e-9
Score:  0.206
Data Source:  BioPlex,STRINGDB
KBTBD7
Tdark
Novelty:  0.4947466
p_int:  0.991365247
p_ni:  0.008633797
p_wrong:  9.56e-7
Data Source:  BioPlex
PTPRK
Tbio
Family:  Enzyme
Novelty:  0.03149943
p_int:  0.806052186
p_ni:  0.193946188
p_wrong:  0.000001627
Data Source:  BioPlex
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.913
Data Source:  STRINGDB
ATP1B2
Tclin
Family:  Transporter
Novelty:  0.02641193
Score:  0.755
Data Source:  STRINGDB
NOX4
Tchem
Family:  Enzyme
Novelty:  0.0009803
Score:  0.754
Data Source:  STRINGDB
HLX
Tbio
Family:  TF
Novelty:  0.00982861
Score:  0.665
Data Source:  STRINGDB
ESRRG
Tchem
Family:  NR
Novelty:  0.00544196
Score:  0.65
Data Source:  STRINGDB
EWSR1
Tbio
Novelty:  0.00068411
Score:  0.629
Data Source:  STRINGDB
SPO11
Tbio
Novelty:  0.00273994
Score:  0.551
Data Source:  STRINGDB
Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
1
1
78.3
FEV/FEC ratio
1
1
1
62.5
body height
1
1
1
62.1
1
1
0
1.3
61
erythrocyte count
1
1
1
52.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
78.3
FEV/FEC ratio
1
62.5
body height
1
62.1
0
1.3
61
erythrocyte count
1
52.7
Find similar targets by:
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 3
VGNC:14122
463586
Macaque
zinc finger protein 3
719069
Mouse
MGI:1929116
56314
Rat
RGD:6489147
100912096
Dog
zinc finger protein 3 [Source:HGNC Symbol;Acc:HGNC:13089]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 3
Macaque
zinc finger protein 3
Mouse
Rat
Dog
zinc finger protein 3 [Source:HGNC Symbol;Acc:HGNC:13089]
Publication Statistics
PubMed Score 8.99
PubMed score by year
PubTator Score 8.19
PubTator score by year