You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ZNF25
Zinc finger protein 25

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000302609
  • ENSP00000302222
  • ENSG00000175395

Symbol
  • KOX19
  • Zfp9
  • KOX19
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.81
gene perturbation
0.71
tissue sample
0.69
virus perturbation
0.64
cell type or tissue
0.6


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.44   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 113   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.44   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 113   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
aging
3
2
3
69.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
aging
3
69.9
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 25
VGNC:12547
466277
Mouse
MGI:99210
22750
Rat
RGD:2293498
100158232
Cow
zinc finger protein 25
101905074
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 25
Mouse
Rat
Cow
zinc finger protein 25
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P17030-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (16)
1 – 10 of 16
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.947
Data Source:  STRINGDB
RANBP3L
Tdark
Novelty:  0.35708446
Score:  0.575
Data Source:  STRINGDB
BRD8
Tbio
Family:  Epigenetic
Novelty:  0.09769287
Score:  0.558
Data Source:  STRINGDB
SCRN1
Tbio
Family:  Enzyme
Novelty:  0.08315012
Score:  0.547
Data Source:  STRINGDB
SUPT3H
Tbio
Novelty:  0.13202683
Score:  0.531
Data Source:  STRINGDB
ZZZ3
Tdark
Family:  TF
Novelty:  0.23862921
Score:  0.52
Data Source:  STRINGDB
ZBTB21
Tbio
Family:  TF
Novelty:  0.16032292
Score:  0.51
Data Source:  STRINGDB
SMARCC2
Tbio
Family:  TF; Epigenetic
Novelty:  0.02625321
Score:  0.484
Data Source:  STRINGDB
RASGEF1C
Tdark
Novelty:  0.93266395
Score:  0.445
Data Source:  STRINGDB
NFIX
Tbio
Family:  TF
Novelty:  0.00785778
Score:  0.44
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.44

PubMed score by year
PubTator Score  1.26

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer