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Tdark
ZNF708
Zinc finger protein 708

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356929
  • ENSP00000349401
  • ENSG00000182141

Symbol
  • KOX8
  • ZNF15
  • ZNF15L1
  • KOX8
  • ZNF15
  • ZNF15L1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.64
cell line
0.6
transcription factor
0.52
microRNA
0.5
histone modification site profile
0.45


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.32   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 93   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.32   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.2
6.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
6.6
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 708
VGNC:2130
468791
Macaque
zinc finger protein 708
693803
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 708
Macaque
zinc finger protein 708
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P17019-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (15)
1 – 10 of 15
ANKRD36B
Tdark
Novelty: 2.44907149
p_int: 0.999982115
p_ni: 0.000016092
p_wrong: 0.000001793
Data Source: BioPlex
ZKSCAN8
Tbio
Family: TF
Novelty: 0.17881042
p_int: 0.999879908
p_ni: 0.000063704
p_wrong: 0.000056388
Data Source: BioPlex
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
p_int: 0.998629046
p_ni: 0.000003621
p_wrong: 0.001367333
Score: 0.925
Data Source: BioPlex,STRINGDB
ZNF653
Tbio
Family: TF
Novelty: 1.467544
p_int: 0.923094401
p_ni: 0.000568756
p_wrong: 0.076336843
Data Source: BioPlex
KRTAP19-2
Tdark
Novelty: 5.72307692
Score: 0.585
Data Source: STRINGDB
KIAA1958
Tdark
Novelty: 1.68951686
Score: 0.581
Data Source: STRINGDB
CREG2
Tdark
Novelty: 0.83142703
Score: 0.51
Data Source: STRINGDB
NICN1
Tdark
Novelty: 0.32909597
Score: 0.51
Data Source: STRINGDB
SREK1IP1
Tdark
Novelty: 1.39429464
Score: 0.491
Data Source: STRINGDB
SFXN3
Tbio
Novelty: 0.18698456
Score: 0.473
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.32

PubMed score by year
PubTator Score  1.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer