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Tdark
ZNF250
Zinc finger protein 250

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000292579
  • ENSP00000292579
  • ENSG00000196150
  • ENST00000417550
  • ENSP00000393442

Symbol
  • ZNF647
  • ZFP647
  • ZNF647
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.94
histone modification site profile
0.89
disease perturbation
0.68
microRNA
0.66
small molecule perturbation
0.65


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.31   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 8   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.31   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 8   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
21.5
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 250
704805
Mouse
MGI:3052806
239546
Rat
RGD:1308203
362948
Dog
zinc finger protein 250
VGNC:48681
100683615
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 250
Mouse
Rat
Dog
zinc finger protein 250
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P15622-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (16)
1 – 10 of 16
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.999998171
p_ni:  0.000001829
Score:  0.944
Data Source:  BioPlex,STRINGDB
SPINT1
Tbio
Family:  Enzyme
Novelty:  0.00930324
p_int:  0.999816641
p_ni:  0.000061395
p_wrong:  0.000121963
Score:  0.685
Data Source:  BioPlex,STRINGDB
TPM2
Tbio
Novelty:  0.00406572
p_int:  0.983344452
p_ni:  0.016655546
p_wrong:  2e-9
Score:  0.245
Data Source:  BioPlex,STRINGDB
LTF
Tbio
Novelty:  0.00114254
p_int:  0.913844746
p_ni:  0.086155254
Score:  0.219
Data Source:  BioPlex,STRINGDB
ZC4H2
Tbio
Novelty:  0.04969464
Score:  0.686
Data Source:  STRINGDB
RPS7
Tbio
Novelty:  0.00745987
Score:  0.669
Data Source:  STRINGDB
ZNF428
Tdark
Novelty:  3.23887218
Score:  0.537
Data Source:  STRINGDB
FBXL6
Tdark
Novelty:  0.33416595
Score:  0.475
Data Source:  STRINGDB
WDR97
Tdark
Novelty:  11.62556618
Score:  0.469
Data Source:  STRINGDB
TMEM249
Tdark
Novelty:  11.31914894
Score:  0.468
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.31

PubMed score by year
PubTator Score  0.82

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer