Protein Summary
This protein is a minor sialoglycoprotein in human erythrocyte membranes. The protein encoded by this gene is a sialoglycoprotein and a type I membrane protein. It is a member of a gene family with GPA and GPB genes. This encoded protein might carry the M blood group antigen. GYPA, GYPB, and GYPE are organized in tandem on chromosome 4. This gene might have derived from an ancestral gene common to the GPB gene by gene duplication. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
- ENST00000358615
- ENSP00000351430
- ENSG00000197465
- ENST00000437468
- ENSP00000400698
- GPE
- GPE
- MNS
- GYPA
- MiIX
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.85 | ||
tissue sample | 0.66 | ||
microRNA | 0.6 | ||
co-expressed gene | 0.52 | ||
disease | 0.5 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 848.62 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 37 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 848.62 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 37 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0