FDPS
Farnesyl pyrophosphate synthase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.88 | ||
kinase perturbation | 0.81 | ||
ligand (chemical) | 0.8 | ||
transcription factor perturbation | 0.74 | ||
small molecule perturbation | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of gene expression by SREBF (SREBP) | ||||
Reactome | Cholesterol biosynthesis | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | Metabolism of steroids | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of gene expression by SREBF (SREBP) | ||||
Cholesterol biosynthesis | ||||
Metabolism | ||||
Metabolism of lipids | ||||
Metabolism of steroids | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
reticulocyte measurement | 3 | 2 | 4 | 93.8 | |||||
2 | 2 | 0 | 1.3 | 90.8 | |||||
reticulocyte count | 6 | 2 | 10 | 89 | |||||
red blood cell distribution width | 2 | 2 | 2 | 85.2 | |||||
hemoglobin measurement | 1 | 2 | 2 | 83.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
reticulocyte measurement | 4 | 93.8 | |||||
0 | 1.3 | 90.8 | |||||
reticulocyte count | 10 | 89 | |||||
red blood cell distribution width | 2 | 85.2 | |||||
hemoglobin measurement | 2 | 83.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | farnesyl diphosphate synthase | VGNC:539 | 457366 | |||||
Macaque | farnesyl diphosphate synthase | 717761 | ||||||
Mouse | MGI:104888 | 110196 | ||||||
Rat | RGD:68953 | 83791 | ||||||
Dog | farnesyl diphosphate synthase | VGNC:40812 | 480129 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | farnesyl diphosphate synthase | |||||
Macaque | farnesyl diphosphate synthase | |||||
Mouse | ||||||
Rat | ||||||
Dog | farnesyl diphosphate synthase | |||||
PMID | Year | Title |
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