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Tdark
CCDC130
Coiled-coil domain-containing protein 130

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000221554
  • ENSP00000221554
  • ENSG00000104957
  • ENST00000586600
  • ENSP00000465776
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.9
kinase perturbation
0.81
histone modification site profile
0.8
cell type or tissue
0.72
disease perturbation
0.62


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.06   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.06   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 130
VGNC:3639
747288
Macaque
coiled-coil domain containing 130
718398
Mouse
MGI:1914986
67736
Rat
RGD:1307598
304656
Dog
coiled-coil domain containing 130
VGNC:38791
484915
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 130
Macaque
coiled-coil domain containing 130
Mouse
Rat
Dog
coiled-coil domain containing 130
Pathways (34)
Items per page:
1 – 5 of 34
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Ectoderm Differentiation
WikiPathways
Ectoderm Differentiation
WikiPathways
Ectoderm Differentiation
WikiPathways
Ectoderm Differentiation
WikiPathways
Ectoderm Differentiation
Name
Explore in Pharos
Explore in Source
Ectoderm Differentiation
Ectoderm Differentiation
Ectoderm Differentiation
Ectoderm Differentiation
Ectoderm Differentiation
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Expression Pattern (IEP)
UniProtKB
Protein-Protein Interactions (57)
1 – 10 of 57
KDM8
Tbio
Family: Epigenetic
Novelty: 0.03368031
p_int: 0.999985701
p_ni: 0.000014181
p_wrong: 1.18e-7
Score: 0.823
Data Source: BioPlex,STRINGDB
ZZEF1
Tdark
Novelty: 0.33216648
p_int: 0.998838946
p_ni: 0.001161054
Score: 0.177
Data Source: BioPlex,STRINGDB
HECTD3
Tdark
Family: Enzyme
Novelty: 2.20874654
p_int: 0.998173913
p_ni: 0.001826087
Score: 0.159
Data Source: BioPlex,STRINGDB
UBR1
Tbio
Family: Enzyme
Novelty: 0.00998888
p_int: 0.947501333
p_ni: 0.052498667
Data Source: BioPlex
PPP2R2D
Tbio
Family: Enzyme
Novelty: 0.0658328
p_int: 0.933420194
p_ni: 0.066579806
Data Source: BioPlex
RCCD1
Tbio
Novelty: 0.07481641
p_int: 0.849098848
p_ni: 0.150901152
Score: 0.674
Data Source: BioPlex,STRINGDB
UBR2
Tbio
Family: Enzyme
Novelty: 0.03126228
p_int: 0.76770833
p_ni: 0.23229167
Score: 0.195
Data Source: BioPlex,STRINGDB
BUD31
Tbio
Novelty: 0.13364384
Score: 0.85
Data Source: STRINGDB
CDC5L
Tbio
Family: TF
Novelty: 0.00663599
Score: 0.832
Data Source: STRINGDB
CDC40
Tbio
Novelty: 0.03139044
Score: 0.828
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.06

PubMed score by year
PubTator Score  0.25

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer