NCAM1
Neural cell adhesion molecule 1
Protein Summary
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
- ENST00000316851
- ENSP00000318472
- ENSG00000149294
- ENST00000529356
- ENSP00000482205
- ENST00000531044
- ENSP00000484943
- ENST00000621128
- ENSP00000481083
- ENST00000621850
- ENSP00000480774
- NCAM
- CD56
- NCAM
- MSK39
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
PubMedID | 0.98 | ||
transcription factor perturbation | 0.91 | ||
trait | 0.86 | ||
protein domain | 0.85 | ||
cellular component | 0.79 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 5324.25 (req: < 5)
Gene RIFs: 331 (req: <= 3)
Antibodies: 3031 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 5324.25 (req: >= 5)
Gene RIFs: 331 (req: > 3)
Antibodies: 3031 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0