COL6A3
Collagen alpha-3(VI) chain
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.96 | ||
protein domain | 0.85 | ||
disease perturbation | 0.83 | ||
disease | 0.71 | ||
PubMedID | 0.61 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Assembly of collagen fibrils and other multimeric structures | ||||
Reactome | Axon guidance | ||||
Reactome | Collagen biosynthesis and modifying enzymes | ||||
Reactome | Collagen chain trimerization | ||||
Reactome | Collagen formation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Assembly of collagen fibrils and other multimeric structures | ||||
Axon guidance | ||||
Collagen biosynthesis and modifying enzymes | ||||
Collagen chain trimerization | ||||
Collagen formation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 3 | 4 | 6 | 90.9 | |||||
3 | 3 | 2 | 25 | 89.8 | |||||
intraocular pressure measurement | 2 | 3 | 3 | 79.2 | |||||
1 | 1 | 0 | 50 | 76.5 | |||||
5 | 4 | 0 | 1.1 | 64.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 6 | 90.9 | |||||
2 | 25 | 89.8 | |||||
intraocular pressure measurement | 3 | 79.2 | |||||
0 | 50 | 76.5 | |||||
0 | 1.1 | 64.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | collagen type VI alpha 3 chain | VGNC:10726 | 460045 | |||||
Macaque | collagen type VI alpha 3 chain | 694701 | ||||||
Mouse | MGI:88461 | 12835 | ||||||
Dog | collagen type VI alpha 3 chain | VGNC:39481 | 403582 | |||||
Horse | collagen type VI alpha 3 chain | VGNC:16748 | 100066356 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | collagen type VI alpha 3 chain | |||||
Macaque | collagen type VI alpha 3 chain | |||||
Mouse | ||||||
Dog | collagen type VI alpha 3 chain | |||||
Horse | collagen type VI alpha 3 chain | |||||
PMID | Year | Title |
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