You are using an outdated browser. Please upgrade your browser to improve your experience.

Tclin
MS4A1
B-lymphocyte antigen CD20

Protein Summary
Description
This protein may be involved in the regulation of B-cell activation and proliferation. This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000345732
  • ENSP00000314620
  • ENSG00000156738
  • ENST00000389939
  • ENSP00000374589
  • ENST00000528313
  • ENSP00000432270
  • ENST00000534668
  • ENSP00000433277

Symbol
  • CD20
  • B1
  • S7
  • Bp35
  • CD20
  • CVID5
  • MS4A2
  • LEU-16
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological term
0.83
cell line
0.73
kinase
0.63
microRNA
0.56
PubMedID
0.55


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 159.17   (req: < 5)
Gene RIFs: 114   (req: <= 3)
Antibodies: 3294   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 159.17   (req: >= 5)
Gene RIFs: 114   (req: > 3)
Antibodies: 3294   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 5