IGF2R
Cation-independent mannose-6-phosphate receptor
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.99 | ||
disease perturbation | 0.97 | ||
cellular component | 0.94 | ||
virus perturbation | 0.94 | ||
interacting protein | 0.93 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cargo recognition for clathrin-mediated endocytosis | ||||
Reactome | Clathrin-mediated endocytosis | ||||
Reactome | Golgi Associated Vesicle Biogenesis | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cargo recognition for clathrin-mediated endocytosis | ||||
Clathrin-mediated endocytosis | ||||
Golgi Associated Vesicle Biogenesis | ||||
Immune System | ||||
Innate Immune System | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 5 | 16 | 23 | 2.3 | 98.8 | ||||
glomerular filtration rate | 3 | 5 | 6 | 98.6 | |||||
apolipoprotein B measurement | 2 | 13 | 14 | 98.5 | |||||
total cholesterol measurement | 6 | 15 | 21 | 2.4 | 98.5 | ||||
IGF-1 measurement | 1 | 6 | 6 | 92.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
low density lipoprotein cholesterol measurement | 23 | 2.3 | 98.8 | ||||
glomerular filtration rate | 6 | 98.6 | |||||
apolipoprotein B measurement | 14 | 98.5 | |||||
total cholesterol measurement | 21 | 2.4 | 98.5 | ||||
IGF-1 measurement | 6 | 92.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | insulin like growth factor 2 receptor | VGNC:3256 | 463112 | |||||
Macaque | insulin like growth factor 2 receptor | 703220 | ||||||
Mouse | MGI:96435 | 16004 | ||||||
Rat | RGD:2871 | 25151 | ||||||
Dog | insulin like growth factor 2 receptor | VGNC:41901 | 484067 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | insulin like growth factor 2 receptor | |||||
Macaque | insulin like growth factor 2 receptor | |||||
Mouse | ||||||
Rat | ||||||
Dog | insulin like growth factor 2 receptor | |||||
PMID | Year | Title |
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