You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
LAMP1
Lysosome-associated membrane glycoprotein 1

Protein Summary
Description
Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Acts as a receptor for Lassa virus protein. The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000332556
  • ENSP00000333298
  • ENSG00000185896

Symbol
  • LAMPA
  • CD107a
  • LGP120
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
1
cellular component
0.98
interacting protein
0.98
kinase perturbation
0.98
transcription factor binding site profile
0.88


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1668.65   (req: < 5)
Gene RIFs: 49   (req: <= 3)
Antibodies: 1259   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1668.65   (req: >= 5)
Gene RIFs: 49   (req: > 3)
Antibodies: 1259   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0