EGR2
E3 SUMO-protein ligase EGR2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 1 | ||
molecular function | 0.99 | ||
PubMedID | 0.98 | ||
biological process | 0.97 | ||
virus perturbation | 0.94 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of HOX genes during differentiation | ||||
Reactome | Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
Reactome | Developmental Biology | ||||
Reactome | Transcriptional regulation of white adipocyte differentiation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of HOX genes during differentiation | ||||
Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
Developmental Biology | ||||
Transcriptional regulation of white adipocyte differentiation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Direct Assay (IDA) | NTNU_SB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
2 | 2 | 0 | 1.3 | 77.7 | |||||
eosinophil count | 1 | 1 | 1 | 76.1 | |||||
lymphocyte count | 2 | 1 | 2 | 72.3 | |||||
1 | 1 | 0 | 1.7 | 68 | |||||
platelet count | 1 | 1 | 1 | 67.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.3 | 77.7 | |||||
eosinophil count | 1 | 76.1 | |||||
lymphocyte count | 2 | 72.3 | |||||
0 | 1.7 | 68 | |||||
platelet count | 1 | 67.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | early growth response 2 | VGNC:12319 | 745846 | |||||
Macaque | early growth response 2 | 698132 | ||||||
Mouse | MGI:95296 | 13654 | ||||||
Rat | RGD:621608 | 114090 | ||||||
Dog | early growth response 2 | VGNC:51893 | 479219 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | early growth response 2 | |||||
Macaque | early growth response 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | early growth response 2 | |||||
PMID | Year | Title |
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