IRF1
Interferon regulatory factor 1
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
PubMedID | 1 | ||
virus perturbation | 1 | ||
biological process | 0.99 | ||
disease perturbation | 0.93 | ||
transcription factor binding site profile | 0.91 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | Factors involved in megakaryocyte development and platelet production | ||||
Reactome | Hemostasis | ||||
Reactome | Immune System | ||||
Reactome | Interferon Signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytokine Signaling in Immune system | ||||
Factors involved in megakaryocyte development and platelet production | ||||
Hemostasis | ||||
Immune System | ||||
Interferon Signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Mutant Phenotype (IMP) | NTNU_SB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
eosinophil count | 5 | 9 | 10 | 7.1 | 99.7 | ||||
eosinophil percentage of leukocytes | 2 | 5 | 7 | 98.6 | |||||
fibrinogen measurement | 6 | 6 | 6 | 6.8 | 98.5 | ||||
4 | 4 | 1 | 1.2 | 97.2 | |||||
8 | 9 | 1 | 1.1 | 96.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
eosinophil count | 10 | 7.1 | 99.7 | ||||
eosinophil percentage of leukocytes | 7 | 98.6 | |||||
fibrinogen measurement | 6 | 6.8 | 98.5 | ||||
1 | 1.2 | 97.2 | |||||
1 | 1.1 | 96.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | interferon regulatory factor 1 | VGNC:4049 | 107974852 | |||||
Macaque | interferon regulatory factor 1 | 707788 | ||||||
Mouse | MGI:96590 | 16362 | ||||||
Rat | RGD:2920 | 24508 | ||||||
Dog | interferon regulatory factor 1 | VGNC:42091 | 100855872 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | interferon regulatory factor 1 | |||||
Macaque | interferon regulatory factor 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | interferon regulatory factor 1 | |||||
PMID | Year | Title |
---|