GAA
Lysosomal alpha-glucosidase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.89 | ||
transcription factor perturbation | 0.88 | ||
protein domain | 0.85 | ||
disease perturbation | 0.83 | ||
cellular component | 0.8 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Disease | ||||
Reactome | Diseases of carbohydrate metabolism | ||||
Reactome | Diseases of metabolism | ||||
Reactome | Glycogen breakdown (glycogenolysis) | ||||
Reactome | Glycogen metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Disease | ||||
Diseases of carbohydrate metabolism | ||||
Diseases of metabolism | ||||
Glycogen breakdown (glycogenolysis) | ||||
Glycogen metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean reticulocyte volume | 1 | 2 | 2 | 88.6 | |||||
reticulocyte measurement | 3 | 2 | 5 | 87.4 | |||||
reticulocyte count | 7 | 2 | 9 | 87.3 | |||||
mean corpuscular volume | 1 | 1 | 1 | 73 | |||||
1 | 1 | 0 | 1.4 | 68.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean reticulocyte volume | 2 | 88.6 | |||||
reticulocyte measurement | 5 | 87.4 | |||||
reticulocyte count | 9 | 87.3 | |||||
mean corpuscular volume | 1 | 73 | |||||
0 | 1.4 | 68.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | glucosidase alpha, acid | VGNC:9298 | 454940 | |||||
Macaque | glucosidase alpha, acid | 712054 | ||||||
Mouse | MGI:95609 | 14387 | ||||||
Rat | RGD:735227 | 367562 | ||||||
Dog | glucosidase alpha, acid | VGNC:41044 | 483352 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | glucosidase alpha, acid | |||||
Macaque | glucosidase alpha, acid | |||||
Mouse | ||||||
Rat | ||||||
Dog | glucosidase alpha, acid | |||||
PMID | Year | Title |
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