Protein Summary
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. This gene encodes a member of the alpha tubulin family. Tubulin is a major component of microtubules, which are composed of alpha- and beta-tubulin heterodimers and microtubule-associated proteins in the cytoskeleton. Microtubules maintain cellular structure, function in intracellular transport, and play a role in spindle formation during mitosis. [provided by RefSeq, Oct 2011]
- ENST00000321253
- ENSP00000326042
- ENSG00000075886
- KTCN9
- TUBA2
- H2-ALPHA
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0 | ||
biological term | 0 | ||
cell line | 0 | ||
cell type or tissue | 0 | ||
cellular component | 0 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 44.77 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 0 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 44.77 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 0 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (68)
Nearest Tclin Targets (18)
Upstream (9)
Downstream (9)
1 – 5 of 9
Pathways (16)
Reactome (9)
KEGG (5)
WikiPathways (2)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Carboxyterminal post-translational modifications of tubulin | ||||
Reactome | Chaperonin-mediated protein folding | ||||
Reactome | Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | ||||
Reactome | Formation of tubulin folding intermediates by CCT/TriC | ||||
Reactome | Metabolism of proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Carboxyterminal post-translational modifications of tubulin | ||||
Chaperonin-mediated protein folding | ||||
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | ||||
Formation of tubulin folding intermediates by CCT/TriC | ||||
Metabolism of proteins | ||||
Viral Interactions (0)
Gene Ontology Terms (6)
Functions (3)
Components (2)
Processes (1)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations (null)
GWAS Traits (0)
Find similar targets by:
IDG Resources
Orthologs (8)
1 – 5 of 8
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | tubulin, alpha 3e | 736248 | ||||||
Macaque | tubulin alpha 3c | 707215 | ||||||
Mouse | MGI:1095408 | 22147 | ||||||
Rat | RGD:1565155 | 500363 | ||||||
Dog | tubulin alpha-3 chain-like | 477570 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | tubulin, alpha 3e | |||||
Macaque | tubulin alpha 3c | |||||
Mouse | ||||||
Rat | ||||||
Dog | tubulin alpha-3 chain-like | |||||
Publication Statistics
PubMed Score 44.77
PubMed score by year
PubTator Score 2.71
PubTator score by year
Related Publications
Text Mined References (10)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
---|