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Tbio
PET100
Protein PET100 homolog, mitochondrial

Protein Summary
Description
Mitochondrial complex IV, or cytochrome c oxidase, is a large transmembrane protein complex that is part of the respiratory electron transport chain of mitochondria. The small protein encoded by this gene plays a role in the biogenesis of mitochondrial complex IV. This protein localizes to the inner mitochondrial membrane and is exposed to the intermembrane space. Mutations in this gene are associated with mitochondrial complex IV deficiency. This gene has a pseudogene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000594797
  • ENSP00000470539
  • ENSG00000229833

Symbol
  • C19orf79
  • C19orf79
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
cell type or tissue
0.61
tissue
0.59
tissue sample
0.53
cell line
0.45


Related Tools
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ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.25   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 25   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.25   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
PET100 homolog
100610902
Macaque
PET100 homolog
708563
Mouse
MGI:3615306
100503890
Rat
RGD:1585222
688786
Horse
PET100 homolog
VGNC:21317
100066498
Species
Name
OMA
EggNOG
Inparanoid
Chimp
PET100 homolog
Macaque
PET100 homolog
Mouse
Rat
Horse
PET100 homolog
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P0DJ07-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (53)
1 – 10 of 53
NDUFB10
Tclin
Family: Enzyme
Novelty: 0.05791757
Score: 0.837
Data Source: STRINGDB
FAM102B
Tdark
Novelty: 1.44024802
Score: 0.768
Data Source: STRINGDB
RASAL3
Tbio
Novelty: 0.22098972
Score: 0.723
Data Source: STRINGDB
TRAPPC5
Tdark
Novelty: 0.22558077
Score: 0.715
Data Source: STRINGDB
COX6A2
Tbio
Family: Enzyme
Novelty: 0.05368739
Score: 0.713
Data Source: STRINGDB
NDUFA7
Tclin
Family: Enzyme
Novelty: 0.16417588
Score: 0.686
Data Source: STRINGDB
NDUFA6
Tclin
Family: Enzyme
Novelty: 0.01236094
Score: 0.684
Data Source: STRINGDB
UQCR10
Tbio
Novelty: 0.04536078
Score: 0.68
Data Source: STRINGDB
PET117
Tdark
Novelty: 0.59526462
Score: 0.67
Data Source: STRINGDB
COX14
Tbio
Family: Enzyme
Novelty: 0.09340462
Score: 0.66
Data Source: STRINGDB
Publication Statistics
PubMed Score  6.25

PubMed score by year
PubTator Score  8

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer