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Tbio
P0DI83
Ras-related protein Rab-34, isoform NARR

Protein Summary
Description
This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. An alternatively spliced transcript variant produces the nine-amino acid residue-repeats (NARR) protein, which is a functionally distinct nucleolar protein resulting from a different reading frame. [provided by RefSeq, Dec 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000636154
  • ENSP00000490450
  • ENSG00000109113

Symbol
  • NARR
  • RAH
  • NARR
  • RAB39
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.14   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.14   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (2)
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (110)
UNC13B
Tbio
Novelty:  0.00429808
Score:  0.959
Data Source:  STRINGDB
CHM
Tbio
Family:  Enzyme
Novelty:  0.00226278
Score:  0.94
Data Source:  STRINGDB
CHML
Tbio
Family:  Enzyme
Novelty:  0.00509709
Score:  0.938
Data Source:  STRINGDB
RAB2A
Tchem
Family:  Enzyme
Novelty:  0.00629151
Score:  0.936
Data Source:  STRINGDB
RAB4A
Tbio
Family:  Enzyme
Novelty:  0.00423197
Score:  0.934
Data Source:  STRINGDB
RAB2B
Tbio
Family:  Enzyme
Novelty:  0.18567584
Score:  0.934
Data Source:  STRINGDB
RAB11A
Tbio
Family:  Enzyme
Novelty:  0.00153551
Score:  0.934
Data Source:  STRINGDB
RAB25
Tbio
Family:  Enzyme
Novelty:  0.01889483
Score:  0.934
Data Source:  STRINGDB
RAB5A
Tbio
Family:  Enzyme
Novelty:  0.00111347
Score:  0.933
Data Source:  STRINGDB
RAB12
Tbio
Family:  Enzyme
Novelty:  0.05361391
Score:  0.932
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Post-translational protein modification
Reactome
RAB geranylgeranylation
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Post-translational protein modification
RAB geranylgeranylation
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
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Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (14)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular hemoglobin concentration
1
1
2
83.2
mean corpuscular hemoglobin concentration
1
1
2
83.2
reticulocyte count
2
2
4
83
reticulocyte count
2
2
4
83
reticulocyte measurement
1
1
2
58.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular hemoglobin concentration
2
83.2
mean corpuscular hemoglobin concentration
2
83.2
reticulocyte count
4
83
reticulocyte count
4
83
reticulocyte measurement
2
58.4
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
ras-related protein Rab-34
709951
Mouse
MGI:104606
19376
Rat
RGD:1305058
360571
Dog
RAB34, member RAS oncogene family
VGNC:45277
612952
Horse
RAB34, member RAS oncogene family
VGNC:22110
100072072
Species
Name
OMA
EggNOG
Inparanoid
Macaque
ras-related protein Rab-34
Mouse
Rat
Dog
RAB34, member RAS oncogene family
Horse
RAB34, member RAS oncogene family
Publication Statistics
PubMed Score 46.14
PubMed score by year
PubTator Score 28.00
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title