Protein Summary
Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).
- ENST00000394967
- ENSP00000378418
- ENSG00000217236
- ZNF990
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
PubMedID | 0.78 | ||
cell type or tissue | 0.73 | ||
transcription factor binding site profile | 0.65 | ||
histone modification site profile | 0.57 | ||
tissue sample | 0.49 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 264.74 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 20 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 264.74 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 20 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0