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Tbio
GPR89B
Golgi pH regulator B

Protein Summary
Description
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance. GPR89A is a nearly identical copy of the GPR89B gene (MIM 612806).[supplied by OMIM, Jun 2009]
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.73
tissue
0.66
small molecule perturbation
0.51
cellular component
0.48
transcription factor
0.43


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.8   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 51   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.8   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 51   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
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GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
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ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (27)
1 – 10 of 27
ACP6
Tbio
Family:  Enzyme
Novelty:  0.04985294
Score:  0.731
Data Source:  STRINGDB
CHD1L
Tbio
Family:  Enzyme
Novelty:  0.00980287
Score:  0.684
Data Source:  STRINGDB
NBPF11
Tdark
Novelty:  0.85421227
Score:  0.67
Data Source:  STRINGDB
PRKAB2
Tchem
Family:  Enzyme
Novelty:  0.02815065
Score:  0.631
Data Source:  STRINGDB
FMO5
Tbio
Family:  Enzyme
Novelty:  0.05610368
Score:  0.593
Data Source:  STRINGDB
BCL9
Tbio
Novelty:  0.01853613
Score:  0.557
Data Source:  STRINGDB
TMEM63A
Tdark
Family:  IC
Novelty:  0.33131011
Score:  0.542
Data Source:  STRINGDB
NUDT17
Tdark
Novelty:  0.87396148
Score:  0.539
Data Source:  STRINGDB
ANKRD35
Tdark
Novelty:  0.48931139
Score:  0.519
Data Source:  STRINGDB
GPR155
Tbio
Novelty:  0.20783226
Score:  0.485
Data Source:  STRINGDB
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
1
1
1
2.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
urate measurement
1
2.3
Find similar targets by:
Publication Statistics
PubMed Score 16.80
PubMed score by year
PubTator Score 9.50
PubTator score by year