You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ZGLP1
GATA-type zinc finger protein 1

Protein Summary
Description
Transcriptional repressor that plays a central role in somatic cells of the gonad and is required for germ cell development. Able to repress GATA transcription factor function (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000403903
  • ENSP00000384434
  • ENSG00000220201

Symbol
  • GLP1
  • GLP1
  • GLP-1
  • GATAD3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.72
biological process
0.64
tissue sample
0.61
molecular function
0.49
cell line
0.47


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.49   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 97   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.49   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 97   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (10)
GATA6
Tbio
Family:  TF
Novelty:  0.00267511
Score:  0.805
Data Source:  STRINGDB
WIZ
Tbio
Family:  TF
Novelty:  0.04458547
Score:  0.532
Data Source:  STRINGDB
FOXL2
Tbio
Family:  TF
Novelty:  0.00224046
Score:  0.515
Data Source:  STRINGDB
MOS
Tbio
Family:  Kinase
Novelty:  0.05699356
Score:  0.496
Data Source:  STRINGDB
ZBTB32
Tbio
Family:  TF
Novelty:  0.04876778
Score:  0.445
Data Source:  STRINGDB
LSM14B
Tdark
Novelty:  0.31832554
Score:  0.442
Data Source:  STRINGDB
PABPC1L
Tbio
Novelty:  0.04037574
Score:  0.428
Data Source:  STRINGDB
EIF4E1B
Tdark
Novelty:  0.28023341
Score:  0.426
Data Source:  STRINGDB
BOLA2
Tbio
Novelty:  0.18144236
Score:  0.422
Data Source:  STRINGDB
FDX2
Tdark
Novelty:  0.05747769
Score:  0.414
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (41)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
ICAM-1 measurement
2
3
0
13.8
97.6
IGF-1 measurement
1
4
4
96.7
reticulocyte count
7
7
13
95.2
6
5
0
1.2
92
myeloid white cell count
2
2
2
91.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
ICAM-1 measurement
0
13.8
97.6
IGF-1 measurement
4
96.7
reticulocyte count
13
95.2
0
1.2
92
myeloid white cell count
2
91.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger, GATA-like protein 1
745661
Mouse
MGI:3696042
100009600
Rat
RGD:2322460
100360291
Dog
zinc finger, GATA-like protein 1
VGNC:48630
100684009
Cow
zinc finger, GATA-like protein 1
VGNC:37181
782656
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger, GATA-like protein 1
Mouse
Rat
Dog
zinc finger, GATA-like protein 1
Cow
zinc finger, GATA-like protein 1
Publication Statistics
PubMed Score 4.49
PubMed score by year
PubTator Score 0.17
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title