You are using an outdated browser. Please upgrade your browser to improve your experience.

Tchem
SBK3
Uncharacterized serine/threonine-protein kinase SBK3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000612221
  • ENSP00000483467
  • ENSG00000231274

Symbol
  • SGK110
  • SGK110
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.9
tissue
0.69
protein domain
0.58
cell line
0.43
PubMedID
0.38


Related Tools
Dark Kinase Knowledgebase
The Dark Kinase Knowledgebase is an an online compendium of knowledge and experimental results of understudied kinases.
ProKinO
The ProKinO is a protein kinase-specific ontology, which provides a controlled vocabulary of terms, their hierarchy, and relationships unifying sequence, structure, function, mutation and pathway information on kinases.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 18   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 18   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Active Ligands (1)
1 – 1 of 1
CHEMBL388978
chemical structure image
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P0C264-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (7)
1 – 7 of 7
FAM86B1
Tdark
Family: Enzyme
Novelty: 1.47930034
Score: 0.539
Data Source: STRINGDB
TBCK
Tbio
Family: Kinase
Novelty: 0.08568145
Score: 0.511
Data Source: STRINGDB
POMK
Tbio
Family: Kinase
Novelty: 0.09340344
Score: 0.489
Data Source: STRINGDB
DNPEP
Tchem
Family: Enzyme
Novelty: 0.02415651
Score: 0.473
Data Source: STRINGDB
TEX14
Tbio
Family: Kinase
Novelty: 0.08515917
Score: 0.473
Data Source: STRINGDB
PKDCC
Tbio
Family: Kinase
Novelty: 0.02347112
Score: 0.448
Data Source: STRINGDB
TM6SF1
Tdark
Novelty: 0.40815928
Score: 0.439
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.46

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer