DLD
Dihydrolipoyl dehydrogenase, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 0.99 | ||
virus perturbation | 0.94 | ||
disease perturbation | 0.93 | ||
protein domain | 0.92 | ||
molecular function | 0.86 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Branched-chain amino acid catabolism | ||||
Reactome | Citric acid cycle (TCA cycle) | ||||
Reactome | Glycine degradation | ||||
Reactome | Glyoxylate metabolism and glycine degradation | ||||
Reactome | Lysine catabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Branched-chain amino acid catabolism | ||||
Citric acid cycle (TCA cycle) | ||||
Glycine degradation | ||||
Glyoxylate metabolism and glycine degradation | ||||
Lysine catabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 6 | 9 | 10 | 93.4 | |||||
4 | 3 | 0 | 1.1 | 79.3 | |||||
waist-hip ratio | 4 | 8 | 8 | 79.3 | |||||
waist circumference | 1 | 5 | 5 | 74 | |||||
BMI-adjusted waist circumference | 1 | 5 | 5 | 60.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 10 | 93.4 | |||||
0 | 1.1 | 79.3 | |||||
waist-hip ratio | 8 | 79.3 | |||||
waist circumference | 5 | 74 | |||||
BMI-adjusted waist circumference | 5 | 60.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | dihydrolipoamide dehydrogenase | VGNC:13647 | 463861 | |||||
Macaque | dihydrolipoamide dehydrogenase | 700494 | ||||||
Mouse | MGI:107450 | 13382 | ||||||
Rat | RGD:735073 | 298942 | ||||||
Dog | dihydrolipoamide dehydrogenase | VGNC:39976 | 403978 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | dihydrolipoamide dehydrogenase | |||||
Macaque | dihydrolipoamide dehydrogenase | |||||
Mouse | ||||||
Rat | ||||||
Dog | dihydrolipoamide dehydrogenase | |||||
PMID | Year | Title |
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