GNAI3
Guanine nucleotide-binding protein G(k) subunit alpha
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
interacting protein | 1 | ||
molecular function | 0.99 | ||
pathway | 0.89 | ||
kinase perturbation | 0.84 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | ADP signalling through P2Y purinoceptor 12 | ||||
Reactome | Activation of GABAB receptors | ||||
Reactome | Adenylate cyclase inhibitory pathway | ||||
Reactome | Chaperonin-mediated protein folding | ||||
Reactome | Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
ADP signalling through P2Y purinoceptor 12 | ||||
Activation of GABAB receptors | ||||
Adenylate cyclase inhibitory pathway | ||||
Chaperonin-mediated protein folding | ||||
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
apolipoprotein B measurement | 2 | 12 | 12 | 98.3 | |||||
low density lipoprotein cholesterol measurement | 2 | 9 | 10 | 96.7 | |||||
body mass index | 13 | 4 | 23 | 95.8 | |||||
total cholesterol measurement | 1 | 6 | 6 | 92.2 | |||||
self reported educational attainment | 4 | 4 | 3 | 6.3 | 90.3 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
apolipoprotein B measurement | 12 | 98.3 | |||||
low density lipoprotein cholesterol measurement | 10 | 96.7 | |||||
body mass index | 23 | 95.8 | |||||
total cholesterol measurement | 6 | 92.2 | |||||
self reported educational attainment | 3 | 6.3 | 90.3 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | G protein subunit alpha i3 | VGNC:8327 | 457093 | |||||
Macaque | G protein subunit alpha i3 | 699310 | ||||||
Mouse | MGI:95773 | 14679 | ||||||
Rat | RGD:2714 | 25643 | ||||||
Dog | G protein subunit alpha i3 | VGNC:41303 | 611810 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | G protein subunit alpha i3 | |||||
Macaque | G protein subunit alpha i3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | G protein subunit alpha i3 | |||||
PMID | Year | Title |
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