ASNS
Asparagine synthetase [glutamine-hydrolyzing]
Protein Summary
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
- ENST00000175506
- ENSP00000175506
- ENSG00000070669
- ENST00000394308
- ENSP00000377845
- ENST00000394309
- ENSP00000377846
- ENST00000422745
- ENSP00000414901
- ENST00000437628
- ENSP00000414379
- ENST00000444334
- ENSP00000406994
- ENST00000455086
- ENSP00000408472
- TS11
- TS11
- ASNSD
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
disease perturbation | 1 | ||
kinase perturbation | 0.99 | ||
PubMedID | 0.99 | ||
gene perturbation | 0.98 | ||
transcription factor perturbation | 0.97 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 411.17 (req: < 5)
Gene RIFs: 49 (req: <= 3)
Antibodies: 328 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 411.17 (req: >= 5)
Gene RIFs: 49 (req: > 3)
Antibodies: 328 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 20
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 3
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0