SERPINA6
Corticosteroid-binding globulin
Protein Summary
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events. [provided by RefSeq, Jul 2008]
- ENST00000341584
- ENSP00000342850
- ENSG00000170099
- ENST00000621384
- ENSP00000484501
- ENSG00000277405
- CBG
- CBG
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
drug | 0.81 | ||
cell type or tissue | 0.76 | ||
disease | 0.63 | ||
gene perturbation | 0.6 | ||
biological term | 0.55 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2203.11 (req: < 5)
Gene RIFs: 49 (req: <= 3)
Antibodies: 452 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2203.11 (req: >= 5)
Gene RIFs: 49 (req: > 3)
Antibodies: 452 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 9
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drugs: 12