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Tdark
ACYP1
Acylphosphatase-1

Protein Summary
Description
Its physiological role is not yet clear. This gene is a member of the acylphosphatase family. The encoded protein is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated and described based on their tissue localization: erythrocyte (common) type acylphosphatase encoded by this gene, and muscle type acylphosphatase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000238618
  • ENSP00000238618
  • ENSG00000119640
  • ENST00000357971
  • ENSP00000350655
  • ENST00000555694
  • ENSP00000451581

Symbol
  • ACYPE
  • ACYPE
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.83
histone modification site profile
0.66
tissue sample
0.66
transcription factor binding site profile
0.64
pathway
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.44   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 180   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.44   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 180   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (6)
1 – 5 of 6
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (32)
1 – 10 of 32
ACSS2
Tbio
Family: Enzyme
Novelty: 0.00496109
Score: 0.9
Data Source: STRINGDB
ACOT12
Tbio
Family: Enzyme
Novelty: 0.04948162
Score: 0.9
Data Source: STRINGDB
ACSS1
Tbio
Family: Enzyme
Novelty: 0.03182902
Score: 0.9
Data Source: STRINGDB
ACYP2
Tbio
Family: Enzyme
Novelty: 0.0336735
Score: 0.808
Data Source: STRINGDB
ALDH9A1
Tbio
Family: Enzyme
Novelty: 0.02297759
Score: 0.703
Data Source: STRINGDB
ALDH3A2
Tbio
Family: Enzyme
Novelty: 0.00609975
Score: 0.672
Data Source: STRINGDB
ALDH1B1
Tbio
Family: Enzyme
Novelty: 0.02160629
Score: 0.67
Data Source: STRINGDB
ALDH2
Tclin
Family: Enzyme
Novelty: 0.00094367
Score: 0.658
Data Source: STRINGDB
ALDH7A1
Tbio
Family: Enzyme
Novelty: 0.00101341
Score: 0.652
Data Source: STRINGDB
SUCO
Tdark
Novelty: 0.00152456
Score: 0.626
Data Source: STRINGDB
Publication Statistics
PubMed Score  4.44

PubMed score by year
PubTator Score  2.15

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer