UROD
Uroporphyrinogen decarboxylase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.96 | ||
histone modification site profile | 0.9 | ||
transcription factor perturbation | 0.88 | ||
transcription factor binding site profile | 0.74 | ||
tissue sample | 0.7 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Heme biosynthesis | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of porphyrins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Heme biosynthesis | ||||
Metabolism | ||||
Metabolism of porphyrins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 1 | 1 | 1 | 15.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted hip circumference | 1 | 15.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | uroporphyrinogen decarboxylase | VGNC:1719 | 456541 | |||||
Macaque | uroporphyrinogen decarboxylase | 705166 | ||||||
Mouse | MGI:98916 | 22275 | ||||||
Rat | RGD:3946 | 29421 | ||||||
Dog | uroporphyrinogen decarboxylase | VGNC:48169 | 475378 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | uroporphyrinogen decarboxylase | |||||
Macaque | uroporphyrinogen decarboxylase | |||||
Mouse | ||||||
Rat | ||||||
Dog | uroporphyrinogen decarboxylase | |||||
PMID | Year | Title |
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