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Tbio
CLEC3B
Tetranectin

Protein Summary
Description
Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296130
  • ENSP00000296130
  • ENSG00000163815

Symbol
  • TNA
  • TN
  • TNA
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.83
disease perturbation
0.68
tissue sample
0.68
cellular component
0.62
protein domain
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 284.26   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 331   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 284.26   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 331   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (39)
ECM1
Tbio
Novelty:  0.00518679
Score:  0.933
Data Source:  STRINGDB
SPP2
Tbio
Novelty:  0.04515855
Score:  0.933
Data Source:  STRINGDB
SELENOP
Tbio
Novelty:  0.00194637
Score:  0.933
Data Source:  STRINGDB
TIMP3
Tbio
Family:  Enzyme
Novelty:  0.00134742
Score:  0.913
Data Source:  STRINGDB
ITIH4
Tbio
Novelty:  0.00032471
Score:  0.911
Data Source:  STRINGDB
APOH
Tbio
Novelty:  0.00049117
Score:  0.91
Data Source:  STRINGDB
FAM3C
Tbio
Novelty:  0.04598347
Score:  0.907
Data Source:  STRINGDB
ITIH3
Tbio
Novelty:  0.04201144
Score:  0.904
Data Source:  STRINGDB
RARRES2
Tbio
Novelty:  0.0029178
Score:  0.904
Data Source:  STRINGDB
LGALS3BP
Tbio
Novelty:  0.0025302
Score:  0.902
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Hemostasis (R-HSA-109582)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Hemostasis
Reactome
Platelet activation, signaling and aggregation
Reactome
Platelet degranulation
Reactome
Response to elevated platelet cytosolic Ca2+
Name
Explore in Pharos
Explore in Source
Hemostasis
Platelet activation, signaling and aggregation
Platelet degranulation
Response to elevated platelet cytosolic Ca2+
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
macrophage inflammatory protein 1b measurement
1
2
2
89.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
macrophage inflammatory protein 1b measurement
2
89.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:104540
21922
Dog
C-type lectin domain family 3 member B
VGNC:54591
609596
Horse
C-type lectin domain family 3 member B
VGNC:16604
100630686
Cow
C-type lectin domain family 3 member B
VGNC:27429
515783
Opossum
C-type lectin domain family 3 member B
100619037
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Dog
C-type lectin domain family 3 member B
Horse
C-type lectin domain family 3 member B
Cow
C-type lectin domain family 3 member B
Opossum
C-type lectin domain family 3 member B
Publication Statistics
PubMed Score 284.26
PubMed score by year
PubTator Score 118.91
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title