Tbio CLEC3B Tetranectin

Protein Summary

Description

Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.

Uniprot Accession IDs

• P05452
• Q6FGX6
• TN

Gene Name

• CLEC3B

Ensembl ID

• ENST00000296130
• ENSP00000296130
• ENSG00000163815

Symbol

• TNA
• TN
• TNA

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.83
disease perturbation	0.68
tissue sample	0.68
cellular component	0.62
protein domain	0.58

Protein Classes

PANTHER Classes

Protein / Extracellular Matrix Protein / Extracellular Matrix Structural Protein / Tetranectin

DTO Classes

Protein / Extracellular Structure / Extracellular Matrix Structural Protein / Tetranectin

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 309.43   (req: < 5)

Gene RIFs: 15   (req: <= 3)

Antibodies: 331   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 309.43   (req: >= 5)

Gene RIFs: 15   (req: > 3)

Antibodies: 331   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0