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Tbio
CLEC3B
Tetranectin

Protein Summary
Description
Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296130
  • ENSP00000296130
  • ENSG00000163815

Symbol
  • TNA
  • TN
  • TNA
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.83
disease perturbation
0.68
tissue sample
0.68
cellular component
0.62
protein domain
0.58


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 280.62   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 331   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 280.62   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 331   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:104540
21922
Dog
C-type lectin domain family 3 member B
VGNC:54591
609596
Horse
C-type lectin domain family 3 member B
VGNC:16604
100630686
Cow
C-type lectin domain family 3 member B
VGNC:27429
515783
Opossum
C-type lectin domain family 3 member B
100619037
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Dog
C-type lectin domain family 3 member B
Horse
C-type lectin domain family 3 member B
Cow
C-type lectin domain family 3 member B
Opossum
C-type lectin domain family 3 member B
Protein Structure (4 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-P05452-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 4 of 4
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Pathways (4)
Hemostasis (R-HSA-109582)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Hemostasis
Reactome
Platelet activation, signaling and aggregation
Reactome
Platelet degranulation
Reactome
Response to elevated platelet cytosolic Ca2+
Name
Explore in Pharos
Explore in Source
Hemostasis
Platelet activation, signaling and aggregation
Platelet degranulation
Response to elevated platelet cytosolic Ca2+
Gene Ontology Terms (17)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Physical Interaction (IPI)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (39)
1 – 10 of 39
ECM1
Tbio
Novelty: 0.00518679
Score: 0.933
Data Source: STRINGDB
SPP2
Tbio
Novelty: 0.04515855
Score: 0.933
Data Source: STRINGDB
SELENOP
Tbio
Novelty: 0.00194637
Score: 0.933
Data Source: STRINGDB
TIMP3
Tbio
Family: Enzyme
Novelty: 0.00134742
Score: 0.913
Data Source: STRINGDB
ITIH4
Tbio
Novelty: 0.00032471
Score: 0.911
Data Source: STRINGDB
APOH
Tbio
Novelty: 0.00049117
Score: 0.91
Data Source: STRINGDB
FAM3C
Tbio
Novelty: 0.04598347
Score: 0.907
Data Source: STRINGDB
ITIH3
Tbio
Novelty: 0.04201144
Score: 0.904
Data Source: STRINGDB
RARRES2
Tbio
Novelty: 0.0029178
Score: 0.904
Data Source: STRINGDB
LGALS3BP
Tbio
Novelty: 0.0025302
Score: 0.902
Data Source: STRINGDB
Publication Statistics
PubMed Score  280.62

PubMed score by year
PubTator Score  118.91

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer