CYP11A1
Cholesterol side-chain cleavage enzyme, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
co-expressed gene | 1 | ||
biological process | 0.97 | ||
chemical | 0.92 | ||
virus perturbation | 0.88 | ||
molecular function | 0.81 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Biological oxidations | ||||
Reactome | Cytochrome P450 - arranged by substrate type | ||||
Reactome | Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) | ||||
Reactome | Disease | ||||
Reactome | Diseases of metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Biological oxidations | ||||
Cytochrome P450 - arranged by substrate type | ||||
Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) | ||||
Disease | ||||
Diseases of metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
cups of coffee per day measurement | 1 | 2 | 2 | 65.4 | |||||
apolipoprotein A 1 measurement | 1 | 1 | 1 | 56 | |||||
high density lipoprotein cholesterol measurement | 2 | 1 | 2 | 55.2 | |||||
1 | 1 | 0 | 1.2 | 47.7 | |||||
Cleft palate | 1 | 1 | 0 | 1.2 | 47.7 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
cups of coffee per day measurement | 2 | 65.4 | |||||
apolipoprotein A 1 measurement | 1 | 56 | |||||
high density lipoprotein cholesterol measurement | 2 | 55.2 | |||||
0 | 1.2 | 47.7 | |||||
Cleft palate | 0 | 1.2 | 47.7 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | cholesterol side-chain cleavage enzyme, mitochondrial | 708065 | ||||||
Mouse | MGI:88582 | 13070 | ||||||
Rat | RGD:69325 | 29680 | ||||||
Dog | cytochrome P450 family 11 subfamily A member 1 | VGNC:50329 | 478365 | |||||
Horse | cytochrome P450 family 11 subfamily A member 1 | VGNC:50388 | 100034229 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | cholesterol side-chain cleavage enzyme, mitochondrial | |||||
Mouse | ||||||
Rat | ||||||
Dog | cytochrome P450 family 11 subfamily A member 1 | |||||
Horse | cytochrome P450 family 11 subfamily A member 1 | |||||
PMID | Year | Title |
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