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Tbio
CHGB
Secretogranin-1

Protein Summary
Description
Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000378961
  • ENSP00000368244
  • ENSG00000089199

Symbol
  • SCG1
  • SCG1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.96
PubMedID
0.83
disease perturbation
0.74
histone modification site profile
0.69
transcription factor binding site profile
0.64


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 183.73   (req: < 5)
Gene RIFs: 33   (req: <= 3)
Antibodies: 188   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 183.73   (req: >= 5)
Gene RIFs: 33   (req: > 3)
Antibodies: 188   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromogranin B
VGNC:6079
470034
Macaque
chromogranin B
719171
Mouse
MGI:88395
12653
Rat
RGD:2339
24259
Dog
chromogranin B
VGNC:39212
477165
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromogranin B
Macaque
chromogranin B
Mouse
Rat
Dog
chromogranin B
Pathways (4)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Post-translational protein modification
Reactome
Post-translational protein phosphorylation
Reactome
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Post-translational protein modification
Post-translational protein phosphorylation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Protein-Protein Interactions (174)
1 – 10 of 174
SCG2
Tbio
Novelty: 0.00389492
Score: 0.992
Data Source: STRINGDB
SCG3
Tbio
Novelty: 0.02153066
Score: 0.979
Data Source: STRINGDB
VGF
Tbio
Novelty: 0.00521876
Score: 0.968
Data Source: STRINGDB
PENK
Tbio
Novelty: 0.00074167
Score: 0.958
Data Source: STRINGDB
CHGA
Tbio
Novelty: 0.00033267
Score: 0.943
Data Source: STRINGDB
TGOLN2
Tbio
Novelty: 0.005107
Score: 0.93
Data Source: STRINGDB
CST3
Tbio
Novelty: 0.00021856
Score: 0.928
Data Source: STRINGDB
MFGE8
Tbio
Novelty: 0.00132919
Score: 0.922
Data Source: STRINGDB
FAM20C
Tbio
Family: Enzyme
Novelty: 0.00318966
Score: 0.92
Data Source: STRINGDB
FN1
Tchem
Novelty: 0.00003647
Score: 0.918
Data Source: STRINGDB
Publication Statistics
PubMed Score  183.73

PubMed score by year
PubTator Score  195.73

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer