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Tdark
IFNA16
Interferon alpha-16

Protein Summary
Description
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380216
  • ENSP00000369564
  • ENSG00000147885

Symbol
  • IFN-alphaO
  • IFN-alpha-16
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.82
cell type or tissue
0.58
cell line
0.57
pathway
0.52
tissue
0.48


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.8   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.8   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (49)
Cytokine Signaling in Immune system (R-HSA-1280215)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 10
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cytokine Signaling in Immune system
Reactome
DDX58/IFIH1-mediated induction of interferon-alpha/beta
Reactome
Factors involved in megakaryocyte development and platelet production
Reactome
Hemostasis
Reactome
Immune System
Name
Explore in Pharos
Explore in Source
Cytokine Signaling in Immune system
DDX58/IFIH1-mediated induction of interferon-alpha/beta
Factors involved in megakaryocyte development and platelet production
Hemostasis
Immune System
Gene Ontology Terms (16)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (74)
1 – 10 of 74
IFNA7
Tdark
Novelty: 0.14618009
Score: 0.919
Data Source: STRINGDB
IFNA10
Tbio
Novelty: 0.04848204
Score: 0.919
Data Source: STRINGDB
IFNAR1
Tclin
Novelty: 0.00175488
Score: 0.918
Data Source: STRINGDB
IFNA17
Tbio
Novelty: 0.0030696
Score: 0.916
Data Source: STRINGDB
IFNA14
Tbio
Novelty: 0.17853653
Score: 0.913
Data Source: STRINGDB
IFNA4
Tbio
Novelty: 0.04421984
Score: 0.911
Data Source: STRINGDB
IFNA6
Tbio
Novelty: 0.06253956
Score: 0.91
Data Source: STRINGDB
IFNB1
Tbio
Novelty: 0.00011797
Score: 0.908
Data Source: STRINGDB
IFNA2
Tbio
Novelty: 0.00032935
Score: 0.908
Data Source: STRINGDB
IRF7
Tbio
Family: TF
Novelty: 0.0021839
Score: 0.907
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.80

PubMed score by year
PubTator Score  1.56

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer