Protein Summary
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
- ENST00000380210
- ENSP00000369558
- ENSG00000120235
- IFN-alphaK
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.82 | ||
cell type or tissue | 0.67 | ||
tissue | 0.53 | ||
pathway | 0.52 | ||
phenotype | 0.47 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12.66 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 165 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12.66 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 165 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 14
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Pathways (441)
Reactome (10)
KEGG (22)
PathwayCommons (12)
WikiPathways (397)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 5 of 10
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | DDX58/IFIH1-mediated induction of interferon-alpha/beta | ||||
Reactome | Factors involved in megakaryocyte development and platelet production | ||||
Reactome | Hemostasis | ||||
Reactome | Immune System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytokine Signaling in Immune system | ||||
DDX58/IFIH1-mediated induction of interferon-alpha/beta | ||||
Factors involved in megakaryocyte development and platelet production | ||||
Hemostasis | ||||
Immune System | ||||
Gene Ontology Terms (16)
Functions (2)
Components (2)
Processes (12)
Items per page:
10
1 – 2 of 2
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Protein-Protein Interactions (82)
1 – 10 of 82
IFNA5
Novelty: 0.01718471
p_int: 0.999999792
p_ni: 1.99e-7
p_wrong: 1e-8
Score: 0.852
Data Source: BioPlex,STRINGDB
IFNA1
Novelty: 0.00013873
p_int: 0.999999739
p_ni: 1.3e-8
p_wrong: 2.48e-7
Score: 0.836
Data Source: BioPlex,STRINGDB
IFNA21
Novelty: 0.00852658
p_int: 0.999999456
p_wrong: 5.43e-7
Score: 0.982
Data Source: BioPlex,STRINGDB
IFNA14
Novelty: 0.42599235
p_int: 0.998467302
p_ni: 0.000203693
p_wrong: 0.001329004
Score: 0.99
Data Source: BioPlex,STRINGDB
IFNAR1
Novelty: 0.00224149
Score: 0.936
Data Source: STRINGDB
IRF7
Family: TF
Novelty: 0.00308898
Score: 0.932
Data Source: STRINGDB
IRF3
Family: TF
Novelty: 0.00132895
Score: 0.927
Data Source: STRINGDB
IFNAR2
Novelty: 0.00573978
Score: 0.926
Data Source: STRINGDB
IRF1
Family: TF
Novelty: 0.00077466
Score: 0.923
Data Source: STRINGDB
IRF9
Family: TF
Novelty: 0.01154411
Score: 0.918
Data Source: STRINGDB
Publication Statistics
PubMed Score 12.66
PubMed score by year
PubTator Score 14.91
PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
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