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Tbio
IFNW1
Interferon omega-1

Protein Summary
Description
The protein encoded by this gene is an interferon and possesses antiviral activity. The encoded protein binds to the interferon alpha/beta receptor but not to the interferon gamma receptor. This intronless gene has several pseudogenes spread throughout the genome. [provided by RefSeq, Nov 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380229
  • ENSP00000369578
  • ENSG00000177047
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
0.79
biological process
0.76
tissue sample
0.68
cell line
0.5
phenotype
0.47


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.93   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 118   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.93   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 15
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Pathways (10)
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
KEGG
JAK-STAT signaling pathway
KEGG
Cytokine-cytokine receptor interaction
KEGG
RIG-I-like receptor signaling pathway
Name
Explore in Pharos
Explore in Source
JAK-STAT signaling pathway
Cytokine-cytokine receptor interaction
RIG-I-like receptor signaling pathway
Gene Ontology Terms (16)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Traceable Author Statement (TAS)
ProtInc
Protein-Protein Interactions (58)
1 – 10 of 58
ISG15
Tbio
Novelty: 0.00203781
p_int: 0.99999758
p_ni: 0.000002414
p_wrong: 6e-9
Score: 0.627
Data Source: BioPlex,STRINGDB
IFNAR2
Tclin
Novelty: 0.00453303
Score: 0.984
Data Source: STRINGDB
IFNAR1
Tclin
Novelty: 0.00175488
Score: 0.982
Data Source: STRINGDB
IL10RB
Tbio
Novelty: 0.00880915
Score: 0.741
Data Source: STRINGDB
IFNGR1
Tbio
Novelty: 0.00417244
Score: 0.698
Data Source: STRINGDB
IFNLR1
Tbio
Novelty: 0.01990628
Score: 0.682
Data Source: STRINGDB
IL22RA1
Tbio
Novelty: 0.01107638
Score: 0.675
Data Source: STRINGDB
OSMR
Tbio
Novelty: 0.01554974
Score: 0.673
Data Source: STRINGDB
IL12RB1
Tbio
Novelty: 0.00398741
Score: 0.668
Data Source: STRINGDB
IFNGR2
Tbio
Novelty: 0.01304474
Score: 0.66
Data Source: STRINGDB
Publication Statistics
PubMed Score  6.93

PubMed score by year
PubTator Score  6.15

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer