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Tbio
IFNW1
Interferon omega-1

Protein Summary
Description
The protein encoded by this gene is an interferon and possesses antiviral activity. The encoded protein binds to the interferon alpha/beta receptor but not to the interferon gamma receptor. This intronless gene has several pseudogenes spread throughout the genome. [provided by RefSeq, Nov 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380229
  • ENSP00000369578
  • ENSG00000177047
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
0.79
biological process
0.76
tissue sample
0.68
cell line
0.5
phenotype
0.47


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.76   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 118   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.76   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 118   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 15
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (58)
ISG15
Tbio
Novelty:  0.00203781
p_int:  0.99999758
p_ni:  0.000002414
p_wrong:  6e-9
Score:  0.627
Data Source:  BioPlex,STRINGDB
IFNAR2
Tclin
Novelty:  0.00453303
Score:  0.984
Data Source:  STRINGDB
IFNAR1
Tclin
Novelty:  0.00175488
Score:  0.982
Data Source:  STRINGDB
IL10RB
Tbio
Novelty:  0.00880915
Score:  0.741
Data Source:  STRINGDB
IFNGR1
Tbio
Novelty:  0.00417244
Score:  0.698
Data Source:  STRINGDB
IFNLR1
Tbio
Novelty:  0.01990628
Score:  0.682
Data Source:  STRINGDB
IL22RA1
Tbio
Novelty:  0.01107638
Score:  0.675
Data Source:  STRINGDB
OSMR
Tbio
Novelty:  0.01554974
Score:  0.673
Data Source:  STRINGDB
IL12RB1
Tbio
Novelty:  0.00398741
Score:  0.668
Data Source:  STRINGDB
IFNGR2
Tbio
Novelty:  0.01304474
Score:  0.66
Data Source:  STRINGDB
Nearest Tclin Targets (17)
Explore Nearest Tclin Targets
1 – 5 of 17
LEPR
Tclin
Family:  Other
KEGG Distance:  1
Common Pathways:  2
IL4R
Tclin
Family:  Other
KEGG Distance:  1
Common Pathways:  2
IL6R
Tclin
Family:  Other
KEGG Distance:  1
Common Pathways:  2
CSF3R
Tclin
Family:  Other
KEGG Distance:  1
Common Pathways:  2
MPL
Tclin
Family:  Other
KEGG Distance:  1
Common Pathways:  2
Pathways (10)
Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
KEGG
JAK-STAT signaling pathway
KEGG
Cytokine-cytokine receptor interaction
KEGG
RIG-I-like receptor signaling pathway
Name
Explore in Pharos
Explore in Source
JAK-STAT signaling pathway
Cytokine-cytokine receptor interaction
RIG-I-like receptor signaling pathway
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Horse
interferon omega-2-like
100629859
Cow
interferon-tau-like
509166
Species
Name
OMA
EggNOG
Inparanoid
Horse
interferon omega-2-like
Cow
interferon-tau-like
Publication Statistics
PubMed Score 6.76
PubMed score by year
PubTator Score 6.15
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title