You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
PRM1
Sperm protamine P1

Protein Summary
Description
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000312511
  • ENSP00000310515
  • ENSG00000175646

Symbol
  • P1
  • CT94.1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.6
cell type or tissue
0.46
transcription factor
0.44
tissue
0.43
cell line
0.39


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 97.63   (req: < 5)
Gene RIFs: 27   (req: <= 3)
Antibodies: 56   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 97.63   (req: >= 5)
Gene RIFs: 27   (req: > 3)
Antibodies: 56   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (8)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Protein-Protein Interactions (27)
1 – 10 of 27
PRM2
Tbio
Novelty: 0.0050028
Score: 0.941
Data Source: STRINGDB
TNP1
Tbio
Novelty: 0.01264731
Score: 0.82
Data Source: STRINGDB
TNP2
Tbio
Novelty: 0.01170636
Score: 0.803
Data Source: STRINGDB
NUPR1
Tbio
Novelty: 0.00934603
Score: 0.8
Data Source: STRINGDB
KDM3A
Tchem
Family: Epigenetic
Novelty: 0.0101705
Score: 0.8
Data Source: STRINGDB
KLHL10
Tdark
Novelty: 0.09497583
Score: 0.8
Data Source: STRINGDB
TFAP4
Tbio
Family: TF
Novelty: 0.03155887
Score: 0.649
Data Source: STRINGDB
C1GALT1C1
Tbio
Family: Enzyme
Novelty: 0.01318017
Score: 0.641
Data Source: STRINGDB
PRM3
Tdark
Novelty: 0.03634194
Score: 0.589
Data Source: STRINGDB
SYCP3
Tbio
Novelty: 0.00443901
Score: 0.584
Data Source: STRINGDB
Publication Statistics
PubMed Score  97.63

PubMed score by year
PubTator Score  163.85

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer