TK1
Thymidine kinase, cytosolic
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.97 | ||
transcription factor perturbation | 0.96 | ||
transcription factor binding site profile | 0.82 | ||
interacting protein | 0.81 | ||
biological process | 0.8 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle, Mitotic | ||||
Reactome | G1/S Transition | ||||
Reactome | G1/S-Specific Transcription | ||||
Reactome | Metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell Cycle | ||||
Cell Cycle, Mitotic | ||||
G1/S Transition | ||||
G1/S-Specific Transcription | ||||
Metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
HbA1c measurement | 9 | 16 | 20 | 99.7 | |||||
mean corpuscular volume | 3 | 5 | 5 | 98.4 | |||||
red blood cell distribution width | 4 | 6 | 10 | 98.1 | |||||
reticulocyte measurement | 3 | 7 | 11 | 95.8 | |||||
reticulocyte count | 7 | 11 | 24 | 95.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
HbA1c measurement | 20 | 99.7 | |||||
mean corpuscular volume | 5 | 98.4 | |||||
red blood cell distribution width | 10 | 98.1 | |||||
reticulocyte measurement | 11 | 95.8 | |||||
reticulocyte count | 24 | 95.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | thymidine kinase 1 | VGNC:9711 | 742176 | |||||
Macaque | thymidine kinase 1 | 709403 | ||||||
Mouse | MGI:98763 | 21877 | ||||||
Rat | RGD:621014 | 24834 | ||||||
Dog | thymidine kinase 1 | VGNC:47389 | 100855947 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | thymidine kinase 1 | |||||
Macaque | thymidine kinase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | thymidine kinase 1 | |||||
PMID | Year | Title |
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