Protein Summary
Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
- ENST00000291554
- ENSP00000291554
- ENSG00000160202
- CRYA1
- HSPB4
- CRT1
- CRTL1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase | 0.72 | ||
biological term | 0.64 | ||
cellular component | 0.54 | ||
hub protein | 0.53 | ||
cell type or tissue | 0.52 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 130.91 (req: < 5)
Gene RIFs: 138 (req: <= 3)
Antibodies: 409 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 130.91 (req: >= 5)
Gene RIFs: 138 (req: > 3)
Antibodies: 409 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 10
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 1
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0