COL2A1
Collagen alpha-1(II) chain
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.99 | ||
biological term | 0.94 | ||
PubMedID | 0.92 | ||
disease | 0.86 | ||
phenotype | 0.86 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Assembly of collagen fibrils and other multimeric structures | ||||
Reactome | Collagen biosynthesis and modifying enzymes | ||||
Reactome | Collagen chain trimerization | ||||
Reactome | Collagen formation | ||||
Reactome | Extracellular matrix organization | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Assembly of collagen fibrils and other multimeric structures | ||||
Collagen biosynthesis and modifying enzymes | ||||
Collagen chain trimerization | ||||
Collagen formation | ||||
Extracellular matrix organization | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Non-traceable Author Statement (NAS) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
HbA1c measurement | 3 | 8 | 8 | 96.6 | |||||
hemoglobin measurement | 2 | 3 | 3 | 95.4 | |||||
mean corpuscular volume | 1 | 1 | 1 | 73.6 | |||||
hematocrit | 1 | 2 | 2 | 72.9 | |||||
reticulocyte count | 2 | 2 | 2 | 69.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
HbA1c measurement | 8 | 96.6 | |||||
hemoglobin measurement | 3 | 95.4 | |||||
mean corpuscular volume | 1 | 73.6 | |||||
hematocrit | 2 | 72.9 | |||||
reticulocyte count | 2 | 69.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | collagen type II alpha 1 chain | VGNC:10704 | 451860 | |||||
Mouse | MGI:88452 | 12824 | ||||||
Rat | RGD:2375 | 25412 | ||||||
Dog | collagen type II alpha 1 chain | VGNC:39471 | 403826 | |||||
Horse | collagen type II alpha 1 chain | VGNC:16737 | 791241 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | collagen type II alpha 1 chain | |||||
Mouse | ||||||
Rat | ||||||
Dog | collagen type II alpha 1 chain | |||||
Horse | collagen type II alpha 1 chain | |||||
PMID | Year | Title |
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