CD4
T-cell surface glycoprotein CD4
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.98 | ||
protein domain | 0.97 | ||
virus | 0.89 | ||
molecular function | 0.88 | ||
disease | 0.83 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Alpha-defensins | ||||
Reactome | Antimicrobial peptides | ||||
Reactome | Binding and entry of HIV virion | ||||
Reactome | Cargo recognition for clathrin-mediated endocytosis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Adaptive Immune System | ||||
Alpha-defensins | ||||
Antimicrobial peptides | ||||
Binding and entry of HIV virion | ||||
Cargo recognition for clathrin-mediated endocytosis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | CAFA | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 5 | 2 | 9 | 86.1 | |||||
refractive error measurement | 2 | 1 | 1 | 7.8 | 82.4 | ||||
age at onset | 1 | 1 | 0 | 7.8 | 63.4 | ||||
Myopia | 3 | 1 | 0 | 1.3 | 63.4 | ||||
ganglion cell inner plexiform layer thickness measurement | 1 | 1 | 1 | 58.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
sex hormone-binding globulin measurement | 9 | 86.1 | |||||
refractive error measurement | 1 | 7.8 | 82.4 | ||||
age at onset | 0 | 7.8 | 63.4 | ||||
Myopia | 0 | 1.3 | 63.4 | ||||
ganglion cell inner plexiform layer thickness measurement | 1 | 58.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | CD4 molecule | VGNC:5330 | 450124 | |||||
Macaque | CD4 molecule | 713807 | ||||||
Mouse | MGI:88335 | 12504 | ||||||
Rat | RGD:2306 | 24932 | ||||||
Horse | CD4 molecule | VGNC:16267 | 100052502 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | CD4 molecule | |||||
Macaque | CD4 molecule | |||||
Mouse | ||||||
Rat | ||||||
Horse | CD4 molecule | |||||
PMID | Year | Title |
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