IL2RA
Interleukin-2 receptor subunit alpha
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease | 0.96 | ||
trait | 0.93 | ||
biological process | 0.79 | ||
chemical | 0.79 | ||
phenotype | 0.77 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | FLT3 Signaling | ||||
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Immune System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytokine Signaling in Immune system | ||||
FLT3 Signaling | ||||
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Immune System | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
8 | 9 | 0 | 1.2 | 98.6 | |||||
lymphocyte count | 3 | 3 | 4 | 95.2 | |||||
3 | 4 | 0 | 1.6 | 95 | |||||
7 | 4 | 0 | 1.1 | 92.7 | |||||
interleukin 2 receptor antagonist measurement | 1 | 2 | 2 | 91.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.2 | 98.6 | |||||
lymphocyte count | 4 | 95.2 | |||||
0 | 1.6 | 95 | |||||
0 | 1.1 | 92.7 | |||||
interleukin 2 receptor antagonist measurement | 2 | 91.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | interleukin 2 receptor subunit alpha | VGNC:7232 | 450884 | |||||
Macaque | interleukin 2 receptor subunit alpha | 574300 | ||||||
Mouse | MGI:96549 | 16184 | ||||||
Rat | RGD:2895 | 25704 | ||||||
Dog | interleukin 2 receptor subunit alpha | VGNC:41977 | 403870 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | interleukin 2 receptor subunit alpha | |||||
Macaque | interleukin 2 receptor subunit alpha | |||||
Mouse | ||||||
Rat | ||||||
Dog | interleukin 2 receptor subunit alpha | |||||
PMID | Year | Title |
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