Tbio IFNA2 Interferon alpha-2

Protein Summary

Description

Produced by macrophages, IFN-alpha have antiviral activities. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]

Uniprot Accession IDs

• P01563
• H2DF54
• H2DF55
• P01564
• Q14606
• Q6DJX8
• Q96KI6
• IFN-alpha-2

Gene Name

• IFNA2

Ensembl ID

• ENST00000380206
• ENSP00000369554
• ENSG00000188379

Symbol

• IFNA2A
• IFNA2B
• IFNA2C
• IFNA
• INFA2
• IFNA2B
• IFN-alphaA

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0.99
biological term	0.8
cell type or tissue	0.77
co-expressed gene	0.69
disease	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3041.76   (req: < 5)

Gene RIFs: 92   (req: <= 3)

Antibodies: 988   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3041.76   (req: >= 5)

Gene RIFs: 92   (req: > 3)

Antibodies: 988   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 28

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0