Protein Summary
Prolactin acts primarily on the mammary gland by promoting lactation. This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
- ENST00000306482
- ENSP00000302150
- ENSG00000172179
- GHA1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
chemical | 1 | ||
biological term | 0.91 | ||
gene perturbation | 0.85 | ||
disease | 0.8 | ||
protein domain | 0.58 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12209.87 (req: < 5)
Gene RIFs: 280 (req: <= 3)
Antibodies: 1467 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12209.87 (req: >= 5)
Gene RIFs: 280 (req: > 3)
Antibodies: 1467 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 27
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0